Methods for Allocating Ambiguous Short-reads
نویسندگان
چکیده
منابع مشابه
A Bayesian Assignment Method for Ambiguous Bisulfite Short Reads.
DNA methylation is an epigenetic modification critical for normal development and diseases. The determination of genome-wide DNA methylation at single-nucleotide resolution is made possible by sequencing bisulfite treated DNA with next generation high-throughput sequencing. However, aligning bisulfite short reads to a reference genome remains challenging as only a limited proportion of them (ar...
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ژورنال
عنوان ژورنال: Communications in Information and Systems
سال: 2010
ISSN: 1526-7555,2163-4548
DOI: 10.4310/cis.2010.v10.n2.a1